Viral Vectors: Basic Science and Gene Therapy

Автор(ы):Cid-Arregui Angel
06.10.2007
Год изд.:2000
Описание: This major new volume provides in-depth descriptions of the most relevant viral vector systems currently in use and describes the recent important developments in this field. 37 chapters provide updated methods to prepare the vectors as well as information on their applications to cell biology, neurobiology, gene therapy and more. Ну, а если по-русски: Книга затрагивает вопросы внедрения генов в вектор - молекулу ДНК, способную к автономной репликации и включающую в себя чужеродную ДНК. Рассказывается о свойствах маркеров, многопийности генов, регулируемой экспрессии.
Оглавление:
Viral Vectors: Basic Science and Gene Therapy — обложка книги.
PART I: DNA VIRUS VECTORS
  Introduction to Part I [3]
FAMILY: PARVOVIRIDAE. GENUS: DEPENDOVIRUS (ADENO-ASSOCIATED VIRUSES [AAV])
    1 Gene Transfer with Adeno-Associated Virus Vectors [11]
      A. Srivastava
    2 Strategies for Production of Adeno-Associated Virus Vectors [27]
      D. Grimm and].A. Kleinschmidt
    3 Production and Purification Systems for Recombinant Adeno-Associated Virus Type-2 Vectors [59]
      J.E. Conway, K. Chesnut, I. Zolotukhin, C. apRhys, N. Muzyczka, S. Zolotukhin, and B.J. Byrne
    4 Utility of rAAV for Gene Transfer into Neurons and Other Highly Differentiated Cells [75]
      E.E Terwilliger
    5 Adeno-Associated Virus Vectors for Genetic Immunization [85]
      W.C. Manning and X. Paliard
FAMILY: PARVOVIRIDAE. GENUS: AUTONOMOUS PARVOVIRUSES
    6 Autonomous Parvovirus Vectors [97]
      J.J. Cornells, A. Haag, C. Kornfeld, G. Balboni, A. Y. Dege, B. Neeb, C. Dinsart, and]. Rommelaere
FAMILY: ADENOVIRIDAE. GENUS: MASTADENOVIRUS (MAMMALIAN ADENOVIRUSES)
    7 Molecular Biology of Adenovirus Gene Therapy Vectors [119]
      M.J. Imperiale
    8 Helper-Dependent Adenoviral Vectors: A New Generation of Gene Delivery Vehicles [129]
      M.A. Morsy and L. Chen
    9 Generation of Multiply Deleted Adenovirus Vectors that are Helper Virus Independent [139]
      A. Amalfitano
    10 Adenovirus-Mediated Gene Transfer: In Vivo Persistence of Transduced Cells and Control of Transgene Expression [153]
      R. Rooke, L. Grave, M. Christ, M. Lusky, A. I. Michou, andM. Mehtali
    11 Molecular Conjugate Vectors [171]
      P. Schwarzenberger andJ.K. Kolls
FAMILY: HERPESVIRIDAE. GENUS: ALPHASIMPLEXVIRUS (HERPES SIMPLEX VIRUS)
    12 Construction of Defective Herpes Simplex Recombinant Vectors and Helper-Dependent Amplicons [193]
      A. Cid'Arregui andF. Lim
    13 Gene Transfer Using Helper Virus-Free Herpes Simplex Virus Type 1 Amplicon and Hybrid Amplicon Vectors [211]
      Y. Saeki and C. Fraefel
    14 Stable Gene Transfer Using Hybrid Herpes Simplex-Epstein-Barr Virus Amplicon Vectors [235]
      T.A. Stavropoubs and C.A. Strathdee
    15 Herpesvirus/Retrovirus Chimeras for Gene Delivery [251]
      C. Zaupa andA.L. Epstein
    16 Gene Transfer into Brain Slices from Mouse Embryos Using Herpes Simplex Amplicons [265]
      A. Cid-Arregui and W. Haubensak
    17 Gene Transfer into Cultured Postimplantation Mouse Embryos Using Herpes Simplex Amplicons [277]
      B. Oback, A. Cid-Arregui, and W.B. Huttner
    18 The Use of Herpes Simplex Vectors to Study Alzheimer's Disease Neurodegeneration [295]
      R.L. Neve, D.L. McPhie, andS. Bursztajn
FAMILY: HERPESVIRIDAE. SUBFAMILY: GAMMAHERPESVIRINAE. GENUS: RHADINOVIRUS
    19 Gamma-2-Herpesvirus Vectors for Investigation of Viral Pathogenesis and Experimental Gene Transfer [305]
      S.M. Duboise and]. U. Jung
FAMILY: HERPESVIRIDAE. SUBFAMILY: GAMMAHERPESVIRINAE. GENUS: EPSTEIN-BARR VIRUS
    20 Application of Epstein-Barr Virus and its Genetic Elements to Gene Therapy [325]
      O. Mazda
FAMILY: POXVIRIDAE. SUBFAMILY: ENTOMOPOXVIRINAE. GENUS: ENTOMOPOXVIRUS В
    21 Entomopoxvirus Vectors [341]
      A.L. Bawden, Y. Li, K.J. Glass berg, and R. W. Moyer
FAMILY: BACULOVIRIDAE. GENUS: NUCLEOPOLYHEDROVIRUS (BACULOVIRUS)
    22 High-Efficiency Transduction of Mammalian Cells Using Baculovirus: Practical Aspects [359]
      F.M. Boyceand E.A. Franco
PART II: RNA VIRUS VECTORS
  Introduction to Part II [371]
FAMILY: RETROVIRIDAE. GENUS: ONCOVIRINAE (MLV)
    23 Strategies and Mechanisms for Retrovirus Retargeting [379]
      K. Bupp and M. Roth
    24 Efficient Production of VSV-G-Pseudotyped Retrovirus Vectors Using Stable Packaging Cell Lines [401]
      H. Iba, T.Arai, and M. Ui
    25 Utility of Scaffold Attachment Regions for Enhanced Retroviral Vector Expression in Human Hematopoietic Cells [413]
      I. Plavec and M. Agarwal
    26 Kinetics of Transduction Using Retroviral Vectors: Enhancement by Complex Formation with Cationic Liposomes [431]
      C. Porter
    27 Retrovirally Mediated Genetic Marking of Murine and Human Hematopoietic Repopulating Cells [447]
      A. Bernad, E Varas, M. Ramirez, J. C. Segovia, G. Guenechea, J. Barquinero, and J.A. Bueren
    28 Towards the Genetic Manipulation of the Hematopoietic System: Tumor-Specific Gene Therapy Strategies [467]
      C. Cobaleda and I. Sdnchez-Garria
FAMILY: RETROVIRIDAE. GENUS: LENTIVIRINAE (HIV)
    29 Cellular Transduction by Lentiviral Vectors [485]
      R.E. Sutton
FAMILY: RETROVIRIDAE. GENUS: SPUMAVIRINAE (FOAMY VIRUSES)
    30 Foamy Viruses: Molecular Features and Therapeutic Potential [503]
      C.L Hill and M.O. McClure
    31 Aspects of Foamy Virus Vectors: Host Range and Replication-Competent Vectors [515]
      D. Lindemann, M. Heinkelein, and A. Rethwilm
FAMILY: ORTHOMYXOVIRIDAE. GENUS: INFLUENZA VIRUS
    32 Transfectant Influenza Viruses as Vaccine Vectors [525]
      A. Garda-Sastre
FAMILY: PICORNAVIRIDAE. GENUS: ENTEROVIRUS (POLIOVIRUS)
    33 Picornaviruses as Tools for Antigen Delivery [543]
      S. Mueller and E. Wimmer
FAMILY: TOGAVIRIDAE. GENUS: ALPHAVIRUS (SEMLIKI FOREST VIRUS, SINDBIS VIRUS)
    34 Strategies and Applications of Alphavirus Vectors in Gene Therapy [565]
      S.M. Smith and K.-T. Jeang
    35 Efficient Expression of Proteins with Recombinant Alphaviruses [575]
      A. Cid-Arregui, N. Morales-Peza, V. Juarez, M.J. Garda-Iglesias, and A. Garcia-Carrancd
PART III. GENERAL ISSUES
    36 Gene Therapy Using Viral Vectors: Strategy and Design Issues [597]
      P.A. Lazo and M. Yunta
    37 Biosafety Recommendations for Working with Viral Vectors [609]
      A. Cid-Arregui and V Juarez
INDEX [619]
Формат: djvu
Размер:9103519 байт
Язык:ENG
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