Signal Transduction and Human Disease

Автор(ы):Finkel Toren
06.10.2007
Год изд.:2003
Описание: This publication thoroughly addresses the molecular causes of certain human diseases. The book is divided like many medical textbooks into subspecialty areas. In our case this includes sections in cardiopulmonary disease, oncology, endocrinology, infectious disease, allergy/rheumatology, and neurology/psychiatry. Diseases discussed include among others cancer, asthma, atherosclerosis, diabetes, rheumatoid arthritis, Parkinson disease, and depression. In addition, we outline the current understanding of diverse pathways from MAPK activation in cancer to the role of NF-kB in asthma and arthritis, from JAK/STAT signaling in immune deficiencies to the molecular basis of dysentery.
Оглавление:
Signal Transduction and Human Disease — обложка книги. Обложка книги.
1 Atherosclerosis: Signal Transduction by Oxygen and Nitrogen Radicals [1]
  Jonathan M. Hill, lisa I. Rovira, and Toren Finkel
2 NF-кВ: A Key Signaling Pathway in Asthma [23]
  Stewart j. Levine
3 Molecular Mechanisms of Cancer [71]
  Akrit Sodhi, Silvia Montaner, and J. Silvio Gutkind
4 Apoptotic Pathways in Cancer Progression and Treatment [143]
  Joya Chandra and Scott H. Kaufmann
5 Molecular and Cellular Aspects of Insulin Resistance: Implications for Diabetes [171]
  Derek Le Roith, Michael]. Quon, and Yehiel Zick
6 Dysfunction of G Protein-Regulated Pathways and Endocrine Diseases [201]
  William F. Simonds
7 Bacterial Regulation of the Cytoskeleton [233]
  Jeremy W. Peck, Dora C. Stylianou, and Peter D. Burbelo
8 Bacterial Toxins and Diarrhea [259]
  Walter A. Patton.joel Moss, and Martha Vaughan
9 Molecular Basis of Severe Combined Immunodeficiency: Lessons from Cytokine Signaling Pathways [279]
  Roberto Visconti, Fabio Candotti, and John J. O'Shea
10 Mast Cell-Related Diseases: Genetics, Signaling Pathways, and Novel Therapies [307]
  Michael A. Beaven and Thomas R. Hundley
11 Rheumatology and Signal Transduction [357]
  Keith M. Hull and Daniel L Kastner
12 Molecular Mechanisms of Neurodegenerative Disorders [377]
  Benjamin Wolozin
13 Neurotrophic Signaling in Mood Disorders [411]
  jing Du,Todd D. Gould, and Husseini K. Manji
14 Inhibiting Signaling Pathways Through Rational Drug Design [447]
  James N. Topper and Neill A. Gese
Index [459]
Формат: djvu
Размер:5099528 байт
Язык:ENG
Рейтинг: 198 Рейтинг
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